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He, Chuan

One or more keywords matched the following items that are connected to He, Chuan

Item Type	Name
Concept	Aged, 80 and over
Concept	Adolescent
Concept	Agaricales
Concept	Aged
Concept	Algorithms
Concept	Amino Acid Sequence
Concept	Adult
Concept	Animals
Concept	Animals, Newborn
Concept	B-Lymphocytes
Concept	Base Sequence
Concept	Bacillus anthracis
Concept	Pan troglodytes
Concept	Chlamydomonas
Concept	Carboxy-Lyases
Concept	Bacillus cereus
Concept	Child
Concept	Guinea Pigs
Concept	Cricetulus
Concept	Cross-Linking Reagents
Concept	Child, Preschool
Concept	Edetic Acid
Concept	Leukemia
Concept	Chromatography, High Pressure Liquid
Concept	Chromatography, Liquid
Concept	Drosophila melanogaster
Concept	Infant, Newborn
Concept	Ketoglutaric Acids
Concept	Gram-Positive Bacteria
Concept	Nucleic Acid Hybridization
Concept	Liver Neoplasms
Concept	Escherichia coli
Concept	Infant
Concept	Fourier Analysis
Concept	Light
Concept	Lead
Concept	Macaca mulatta
Concept	Mammals
Concept	Mice, Transgenic
Concept	Molecular Sequence Data
Concept	Mycobacterium tuberculosis
Concept	Mice, Inbred BALB C
Concept	Mice, Inbred C57BL
Concept	Mice, Nude
Concept	Middle Aged
Concept	Repetitive Sequences, Nucleic Acid
Concept	Cricetinae
Concept	Nucleic Acid Conformation
Concept	Ligands
Concept	Liver
Concept	Penicillium
Concept	Polyglutamic Acid
Concept	Regulatory Sequences, Nucleic Acid
Concept	Salmonella typhimurium
Concept	Swine
Concept	Humans
Concept	Linear Models
Concept	Software
Concept	Caenorhabditis elegans
Concept	Sequence Homology, Amino Acid
Concept	Oxo-Acid-Lyases
Concept	Leiomyoma
Concept	Leukemia, Myeloid
Concept	Lysosomes
Concept	Gene Library
Concept	Chlamydomonas reinhardtii
Concept	Leukemia, Myeloid, Acute
Concept	Neoplasm Recurrence, Local
Concept	Bacteriophage T4
Concept	Mice, Knockout
Concept	beta-Lactam Resistance
Concept	Maze Learning
Concept	Nucleic Acid Amplification Techniques
Concept	Protein Transport
Concept	Long Interspersed Nucleotide Elements
Concept	Lanthanoid Series Elements
Concept	Nucleic Acid Denaturation
Concept	Nucleic Acid Heteroduplexes
Concept	Eukaryota
Concept	beta-Lactams
Concept	Amino Acid Substitution
Concept	Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
Concept	Amino Acid Motifs
Concept	Active Transport, Cell Nucleus
Concept	Salicylic Acid
Concept	Databases, Genetic
Concept	Periodicals as Topic
Concept	Plasmodium
Concept	Nucleocytoplasmic Transport Proteins
Concept	Pseudomonas aeruginosa
Concept	Mice
Concept	Saccharomyces cerevisiae
Concept	3T3-L1 Cells
Concept	Ralstonia
Concept	Ubiquitin-Protein Ligases
Concept	Staphylococcus aureus
Concept	Zebrafish
Concept	Leukemia, Promyelocytic, Acute
Concept	Limit of Detection
Concept	Gene Expression Regulation, Leukemic
Concept	Lymphoma, Large B-Cell, Diffuse
Concept	Arabidopsis
Concept	Salmonella enterica
Concept	Small Molecule Libraries
Concept	Cell Lineage
Concept	Editorial Policies
Concept	Seedlings
Concept	Pseudomonas syringae
Concept	Lithostathine
Concept	RNA Transport
Concept	Molecular Sequence Annotation
Concept	Cell Line, Tumor
Concept	Lipid Metabolism
Concept	Myeloid-Lymphoid Leukemia Protein
Concept	Bacterial Secretion Systems
Concept	Cell Line
Concept	Immunoglobulin Light Chains
Concept	Learning
Concept	Liver Diseases
Concept	Luminescent Proteins
Concept	Phylogeny
Concept	Histone-Lysine N-Methyltransferase
Concept	Staining and Labeling
Concept	Sulfenic Acids
Concept	T-Lymphocytes
Concept	Databases, Factual
Concept	Mice, SCID
Concept	Mice, Inbred NOD
Concept	Computational Biology
Concept	Membrane Transport Proteins
Concept	Databases, Nucleic Acid
Concept	Quantitative Trait Loci
Concept	Lipogenesis
Concept	Lymphoid Enhancer-Binding Factor 1
Concept	Young Adult
Concept	Molecular Dynamics Simulation
Academic Article	Spectroscopic insights into lead(II) coordination by the selective lead(II)-binding protein PbrR691.
Academic Article	Capsule anchoring in Bacillus anthracis occurs by a transpeptidation reaction that is inhibited by capsidin.
Academic Article	Genome-wide analysis of N1-methyl-adenosine modification in human tRNAs.
Academic Article	Selective chemical labeling reveals the genome-wide distribution of 5-hydroxymethylcytosine.
Academic Article	A selective fluorescent probe for carbon monoxide imaging in living cells.
Academic Article	Structural and biochemical characterization of N5-carboxyaminoimidazole ribonucleotide synthetase and N5-carboxyaminoimidazole ribonucleotide mutase from Staphylococcus aureus.
Academic Article	The oxidation-sensing regulator (MosR) is a new redox-dependent transcription factor in Mycobacterium tuberculosis.
Academic Article	The structure of the human AGT protein bound to DNA and its implications for damage detection.
Academic Article	A new oxidative sensing and regulation pathway mediated by the MgrA homologue SarZ in Staphylococcus aureus.
Academic Article	Crystal structures of the reduced, sulfenic acid, and mixed disulfide forms of SarZ, a redox active global regulator in Staphylococcus aureus.
Academic Article	Blockade of miR-150 maturation by MLL-fusion/MYC/LIN-28 is required for MLL-associated leukemia.
Academic Article	Synthesis of photoactive analogues of a cystine knot trypsin inhibitor protein.
Academic Article	Binding of ReO4(-) with an engineered MoO4(2-)-binding protein: towards a new approach in radiopharmaceutical applications.
Academic Article	Crystal structures of DNA/RNA repair enzymes AlkB and ABH2 bound to dsDNA.
Academic Article	Selective fluorescent probes for live-cell monitoring of sulphide.
Academic Article	HMGA2/TET1/HOXA9 signaling pathway regulates breast cancer growth and metastasis.
Academic Article	TET1 plays an essential oncogenic role in MLL-rearranged leukemia.
Academic Article	Molecular mechanism of quinone signaling mediated through S-quinonization of a YodB family repressor QsrR.
Academic Article	Hydroxymethylation at gene regulatory regions directs stem/early progenitor cell commitment during erythropoiesis.
Academic Article	N6-methyladenosine-dependent regulation of messenger RNA stability.
Academic Article	ALKBH5 is a mammalian RNA demethylase that impacts RNA metabolism and mouse fertility.
Academic Article	The Pseudomonas aeruginosa multidrug efflux regulator MexR uses an oxidation-sensing mechanism.
Academic Article	Preparation of DNA containing 5-hydroxymethyl-2'-deoxycytidine modification through phosphoramidites with TBDMS as 5-hydroxymethyl protecting group.
Academic Article	Molecular mechanisms of two-component system RhpRS regulating type III secretion system in Pseudomonas syringae.
Academic Article	A new 1'-methylenedisulfide deoxyribose that forms an efficient cross-link to DNA cytosine-5 methyltransferase (DNMT).
Academic Article	Tet-mediated covalent labelling of 5-methylcytosine for its genome-wide detection and sequencing.
Academic Article	An exceptionally selective lead(II)-regulatory protein from Ralstonia metallidurans: development of a fluorescent lead(II) probe.
Academic Article	Iron-catalysed oxidation intermediates captured in a DNA repair dioxygenase.
Academic Article	Oxidative demethylation of 3-methylthymine and 3-methyluracil in single-stranded DNA and RNA by mouse and human FTO.
Academic Article	A diazirine-based nucleoside analogue for efficient DNA interstrand photocross-linking.
Academic Article	AirSR, a [2Fe-2S] cluster-containing two-component system, mediates global oxygen sensing and redox signaling in Staphylococcus aureus.
Academic Article	Staphylococcus aureus CymR is a new thiol-based oxidation-sensing regulator of stress resistance and oxidative response.
Academic Article	Nonenzymatic labeling of 5-hydroxymethylcytosine in nanopore sequencing.
Academic Article	Detection of mismatched 5-hydroxymethyluracil in DNA by selective chemical labeling.
Academic Article	Aureusimines in Staphylococcus aureus are not involved in virulence.
Academic Article	Gold(I)-catalyzed intermolecular addition of phenols and carboxylic acids to olefins.
Academic Article	Using the bias from flow to elucidate single DNA repair protein sliding and interactions with DNA.
Academic Article	N(6)-methyladenosine-dependent RNA structural switches regulate RNA-protein interactions.
Academic Article	High-resolution N(6) -methyladenosine (m(6) A) map using photo-crosslinking-assisted m(6) A sequencing.
Academic Article	Base-resolution maps of 5-formylcytosine and 5-carboxylcytosine reveal genome-wide DNA demethylation dynamics.
Academic Article	A highly sensitive and genetically encoded fluorescent reporter for ratiometric monitoring of quinones in living cells.
Academic Article	Silver-catalyzed intermolecular amination of C--H groups.
Academic Article	The tightly regulated copper window in yeast.
Academic Article	Chemical methods to study protein-nucleic acid interactions.
Academic Article	Quorum-sensing agr mediates bacterial oxidation response via an intramolecular disulfide redox switch in the response regulator AgrA.
Academic Article	How do DNA repair proteins locate potential base lesions? a chemical crosslinking method to investigate O6-alkylguanine-DNA alkyltransferases.
Academic Article	Crystal structures of SlyA protein, a master virulence regulator of Salmonella, in free and DNA-bound states.
Academic Article	Intramolecular additions of alcohols and carboxylic acids to inert olefins catalyzed by silver(I) triflate.
Academic Article	Probing the structure and function of the Escherichia coli DNA alkylation repair AlkB protein through chemical cross-linking.
Academic Article	A non-heme iron-mediated chemical demethylation in DNA and RNA.
Academic Article	Diazirine-based DNA photo-cross-linking probes for the study of protein-DNA interactions.
Academic Article	Oxidative dealkylation DNA repair mediated by the mononuclear non-heme iron AlkB proteins.
Academic Article	Protein cysteine phosphorylation of SarA/MgrA family transcriptional regulators mediates bacterial virulence and antibiotic resistance.
Academic Article	Bioorthogonal labeling of 5-hydroxymethylcytosine in genomic DNA and diazirine-based DNA photo-cross-linking probes.
Academic Article	Nucleic acid modifications with epigenetic significance.
Academic Article	Selective recognition of metal ions by metalloregulatory proteins.
Academic Article	Direct reversal of DNA alkylation damage.
Academic Article	Syntheses of 5-formyl- and 5-carboxyl-dC containing DNA oligos as potential oxidation products of 5-hydroxymethylcytosine in DNA.
Academic Article	Crystal structure of the RNA demethylase ALKBH5 from zebrafish.
Academic Article	Pseudomonas aeruginosa OspR is an oxidative stress sensing regulator that affects pigment production, antibiotic resistance and dissemination during infection.
Academic Article	Nucleic acid oxidation in DNA damage repair and epigenetics.
Academic Article	In the Staphylococcus aureus two-component system sae, the response regulator SaeR binds to a direct repeat sequence and DNA binding requires phosphorylation by the sensor kinase SaeS.
Academic Article	Interaction of human and bacterial AlkB proteins with DNA as probed through chemical cross-linking studies.
Academic Article	Gold-catalyzed organic transformations.
Academic Article	Synthesis of a FTO inhibitor with anticonvulsant activity.
Academic Article	Tet-assisted bisulfite sequencing of 5-hydroxymethylcytosine.
Academic Article	Structure determination of DNA methylation lesions N1-meA and N3-meC in duplex DNA using a cross-linked protein-DNA system.
Academic Article	Gold(I)-catalyzed formation of 3-pyrazolines through cycloaddition of diaziridine to alkynes.
Academic Article	Brønsted acid catalyzed addition of phenols, carboxylic acids, and tosylamides to simple olefins.
Academic Article	Detection of 5-hydroxymethylcytosine in a combined glycosylation restriction analysis (CGRA) using restriction enzyme Taq(a)I.
Academic Article	Engineering bacterial two-component system PmrA/PmrB to sense lanthanide ions.
Academic Article	Live Cell MicroRNA Imaging Using Cascade Hybridization Reaction.
Academic Article	Decoding the transcriptome and DNA methylome of human primordial germ cells.
Academic Article	Preparation of Human Nuclear RNA m6A Methyltransferases and Demethylases and Biochemical Characterization of Their Catalytic Activity.
Academic Article	Efficient and quantitative high-throughput tRNA sequencing.
Academic Article	Inhibition of human copper trafficking by a small molecule significantly attenuates cancer cell proliferation.
Academic Article	Base-resolution detection of N4-methylcytosine in genomic DNA using 4mC-Tet-assisted-bisulfite- sequencing.
Academic Article	Detecting hepatocellular carcinoma in blood.
Academic Article	Weakened N3 Hydrogen Bonding by 5-Formylcytosine and 5-Carboxylcytosine Reduces Their Base-Pairing Stability.
Academic Article	The dynamic N(1)-methyladenosine methylome in eukaryotic messenger RNA.
Academic Article	Nucleic Acid Modifications in Regulation of Gene Expression.
Academic Article	Identification of MLL-fusion/MYC?miR-26?TET1 signaling circuit in MLL-rearranged leukemia.
Academic Article	Structure and mechanism of the essential two-component signal-transduction system WalKR in Staphylococcus aureus.
Academic Article	Nuclear m(6)A Reader YTHDC1 Regulates mRNA Splicing.
Academic Article	A Highly Sensitive and Robust Method for Genome-wide 5hmC Profiling of Rare Cell Populations.
Academic Article	Abundant DNA 6mA methylation during early embryogenesis of zebrafish and pig.
Academic Article	Post-transcriptional gene regulation by mRNA modifications.
Academic Article	The emerging biology of RNA post-transcriptional modifications.
Academic Article	FTO Plays an Oncogenic Role in Acute Myeloid Leukemia as a N6-Methyladenosine RNA Demethylase.
Academic Article	Developing drugs targeting transition metal homeostasis.
Academic Article	YTHDF3 facilitates translation and decay of N6-methyladenosine-modified RNA.
Academic Article	Chemical decaging in living systems.
Academic Article	Nm-seq maps 2'-O-methylation sites in human mRNA with base precision.
Academic Article	Mettl14 Is Essential for Epitranscriptomic Regulation of Striatal Function and Learning.
Academic Article	Chemical Modifications in the Life of an mRNA Transcript.
Academic Article	m6A facilitates hippocampus-dependent learning and memory through YTHDF1.
Academic Article	FOXA1 potentiates lineage-specific enhancer activation through modulating TET1 expression and function.
Academic Article	Ythdc2 is an N6-methyladenosine binding protein that regulates mammalian spermatogenesis.
Academic Article	RNA cytosine methylation and methyltransferases mediate chromatin organization and 5-azacytidine response and resistance in leukaemia.
Academic Article	Differential m6A, m6Am, and m1A Demethylation Mediated by FTO in the Cell Nucleus and Cytoplasm.
Academic Article	m6A mRNA methylation regulates AKT activity to promote the proliferation and tumorigenicity of endometrial cancer.
Academic Article	Single base resolution mapping of 2'-O-methylation sites in human mRNA and in 3' terminal ends of small RNAs.
Academic Article	Identifying the m6A Methylome by Affinity Purification and Sequencing.
Academic Article	YTHDC1 mediates nuclear export of N6-methyladenosine methylated mRNAs.
Academic Article	Author Correction: RNA cytosine methylation and methyltransferases mediate chromatin organization and 5-azacytidine response and resistance in leukaemia.
Academic Article	"Gamete On" for m6A: YTHDF2 Exerts Essential Functions in Female Fertility.
Academic Article	Circadian Clock Regulation of Hepatic Lipid Metabolism by Modulation of m6A mRNA Methylation.
Grant	Mechanisms of Pancreatic Cancer Inhibition by SPARC
Grant	Mechanism of SPARC peptide FSEC inhibition of angiogenesis in neuroblastoma
Academic Article	Inhibition of Copper Transport Induces Apoptosis in Triple-Negative Breast Cancer Cells and Suppresses Tumor Angiogenesis.
Academic Article	Transcriptome-wide Mapping of Internal N7-Methylguanosine Methylome in Mammalian mRNA.
Academic Article	METTL14 is essential for ß-cell survival and insulin secretion.
Academic Article	Jump-seq: Genome-Wide Capture and Amplification of 5-Hydroxymethylcytosine Sites.
Academic Article	m6A mRNA demethylase FTO regulates melanoma tumorigenicity and response to anti-PD-1 blockade.
Academic Article	FMRP Modulates Neural Differentiation through m6A-Dependent mRNA Nuclear Export.
Academic Article	Regulation of Co-transcriptional Pre-mRNA Splicing by m6A through the Low-Complexity Protein hnRNPG.
Academic Article	Prognostic implications of 5-hydroxymethylcytosines from circulating cell-free DNA in diffuse large B-cell lymphoma.
Academic Article	The RNA-binding protein FMRP facilitates the nuclear export of N6-methyladenosine-containing mRNAs.
Academic Article	5-Hydroxymethylcytosine Profiles in Circulating Cell-Free DNA Associate with Disease Burden in Children with Neuroblastoma.
Academic Article	m6A mRNA Methylation Is Essential for Oligodendrocyte Maturation and CNS Myelination.
Academic Article	Keth-seq for transcriptome-wide RNA structure mapping.
Academic Article	DNA 5-Methylcytosine-Specific Amplification and Sequencing.
Academic Article	YTHDF2 promotes mitotic entry and is regulated by cell cycle mediators.
Academic Article	REPIC: a database for exploring the N6-methyladenosine methylome.
Award or Honor Receipt	ACS Chemical Biology Lectureship
Academic Article	Control of Early B Cell Development by the RNA N6-Methyladenosine Methylation.
Academic Article	Genetic analyses support the contribution of mRNA N6-methyladenosine (m6A) modification to human disease heritability.
Academic Article	A New Model of Spontaneous Colitis in Mice Induced by Deletion of an RNA m6A Methyltransferase Component METTL14 in T Cells.
Academic Article	Direct DNA crosslinking with CAP-C uncovers transcription-dependent chromatin organization at high resolution.
Academic Article	LEAD-m6 A-seq for Locus-Specific Detection of N6 -Methyladenosine and Quantification of Differential Methylation.
Academic Article	Alterations of 5-hydroxymethylation in circulating cell-free DNA reflect molecular distinctions of subtypes of non-Hodgkin lymphoma.
Academic Article	N6 -methyladenosine modification of lncRNA Pvt1 governs epidermal stemness.
Academic Article	Autophagy of the m6A mRNA demethylase FTO is impaired by low-level arsenic exposure to promote tumorigenesis.
Academic Article	Wnt signaling pathway involvement in genotypic and phenotypic variations in Waardenburg syndrome type 2 with MITF mutations.
Academic Article	Identification and functional analysis of a novel mutation in the SOX10 gene associated with Waardenburg syndrome type IV.
Academic Article	METTL14 facilitates global genome repair and suppresses skin tumorigenesis.
Academic Article	HRD1-mediated METTL14 degradation regulates m6A mRNA modification to suppress ER proteotoxic liver disease.
Academic Article	KAS-seq: genome-wide sequencing of single-stranded DNA by N3-kethoxal-assisted labeling.
Academic Article	Utility of Perioperative Measurement of Cell-Free DNA and Circulating Tumor DNA in Informing the Prognosis of GI Cancers: A Systematic Review.
Academic Article	FTO mediates LINE1 m6A demethylation and chromatin regulation in mESCs and mouse development.
Academic Article	spKAS-seq reveals R-loop dynamics using low-input materials by detecting single-stranded DNA with strand specificity.
Academic Article	Detection of m6A RNA modifications at single-nucleotide resolution using m6A-selective allyl chemical labeling and sequencing.
Academic Article	Genome-wide profiling of 5-hydroxymethylcytosines in circulating cell-free DNA reveals population-specific pathways in the development of multiple myeloma.
Academic Article	N6-adenomethylation of GsdmC is essential for Lgr5+ stem cell survival to maintain normal colonic epithelial morphogenesis.
Academic Article	The mechanism underlying redundant functions of the YTHDF proteins.
Academic Article	m6A-SAC-seq for quantitative whole transcriptome m6A profiling.
Concept	Copper-transporting ATPases
Concept	Cell-Free Nucleic Acids
Concept	Retinoic Acid Receptor alpha
Concept	Nedd4 Ubiquitin Protein Ligases
Concept	RNA, Long Noncoding
Concept	Aminobenzoates
Concept	Gene Ontology
Concept	Microbiota
Concept	Spatial Learning
Grant	Discovering the epigenetics of RNA modifications
Grant	RNA methylation and regulatory T cells
Grant	Interrogation of dynamic RNA modifications in beta cells in type 1 diabetes
Grant	Recognition and mechanism of N6-methyl adenosine modifications
Grant	Global Cysteine Modifications in Human Pathogens
Grant	Predoctoral Training Program in Chemistry and Biology - Renewal 01
Grant	Direct Oxidative Nucleic Acids Demethylation
Grant	Labeling and sequencing of 5hmC and 5mC in DNA-Renewal
Grant	Base-resolution sequencing of m6A in RNA
Grant	Direct Oxidative Nucleic Acids Demethylation
Academic Article	Splice epitranscriptomics and DNA damage repair together: ALKBH5-m6A-SF3B1 regulation in leukemic transformation.
Academic Article	Genome-Wide Mapping Implicates 5-Hydroxymethylcytosines in Diabetes Mellitus and Alzheimer's Disease.
Academic Article	YTHDF2/m6 A/NF-?B axis controls anti-tumor immunity by regulating intratumoral Tregs.
Academic Article	YTHDF2 inhibition potentiates radiotherapy antitumor efficacy.
Academic Article	RBFOX2 recognizes N6-methyladenosine to suppress transcription and block myeloid leukaemia differentiation.
Academic Article	Adrenergic and mesenchymal signatures are identifiable in cell-free DNA and correlate with metastatic disease burden in children with neuroblastoma.
Academic Article	Analysis of genome-wide 5-hydroxymethylation of blood samples stored in different anticoagulants: opportunities for the expansion of clinical resources for epigenetic research.
Academic Article	FMRP phosphorylation modulates neuronal translation through YTHDF1.
Academic Article	Author Correction: Light-induced LLPS of the CRY2/SPA1/FIO1 complex regulating mRNA methylation and chlorophyll homeostasis in Arabidopsis.
Academic Article	Light-induced LLPS of the CRY2/SPA1/FIO1 complex regulating mRNA methylation and chlorophyll homeostasis in Arabidopsis.
Academic Article	5-Hydroxymethylcytosine signals in serum are a predictor of chemoresistance in high-grade serous ovarian cancer.
Academic Article	Bromodomain-Containing Protein 9 Regulates Signaling Pathways and Reprograms the Epigenome in Immortalized Human Uterine Fibroid Cells.
Academic Article	5-Hydroxymethylcytosine Profiling of Cell-Free DNA Identifies Bivalent Genes That Are Prognostic of Survival in High-Risk Neuroblastoma.

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